The social capital has an important effect on health behaviors of people in society. Therefore, evaluate the components of social capital in women-headed households (WHH) in each community due to vulnerability and the lack of socio-economic background seems necessary. This study conducted to investigate the components of social capital in WHH and its effects on demographic variables by using confirmation analysis. Methods: This cross-sectional study was performed by convenience sampling method on 300 WHH. This was designed to all females who referred to Tehran Municipality (2 District), by using World Bank’s Social Capital Questionnaire (SC- IQ). This tool composed of 6 components within 27 questions. Data was analyzed by confirmation analysis using AMOS software. Results: The mean age of participants was 40.6±9.5 years. The majority of WHH (60.3%) were unemployed. In the confirmatory analysis, income and education have the most impact on social capital of WHH. In addition, the education had a positive association with almost all components but has negative correlation with participating in-group work component. The results showed that among the components of social capital, participation in team work was significantly associated with the education. Also, there was a significant relationship between income and all components of social capital except political empowerment. Conclusion: Income and education had a strong effect on social capital in WHH. Hence, by providing opportunities for improvement in these indicators, may improve the physical, psychological and social health and ultimately diminish the negative burden resulting from these vulnerable groups in the society.