This study discusses the possible application of combined modalities of computer-mediated communication (CMC) tools, namely Email and Skype to foster learner autonomy out of “Freshman English” class and thus facilitate these freshman undergraduates to make transition from high school to university. In order to reach the goal I designed for the course, I involved my EFL students in an out-of-class cross-cultural CMC project, which integrates interactions with native speakers of the target language into language learning and language use autonomously. Data were obtained from students through interviews, reflective diaries and a questionnaire given out at the end of the term. The findings from this study indicated that 1) both the teacher’s and keypals’ supports and encouragements were effective and necessary; 2) good learning habits, taking responsibility for their own learning, motivation for success, effective learning strategies and self-confidence played vital roles in this style of learning process; 3) the participants in this study overwhelmingly chose the synchronous communication as their preferred form of CMC; and 4) they would rather initiate and carry on contact with their international key pals rather than with their classmates.