Concentration of drugs in blood might exceed toxicity level or come below effective level. In addition, side effects of some drugs are not negligible. The present study is an attempt to propose a simple, easy, and environmental friendly method to survey controlled absorption and desorption of medicine using ultrasonic hydrogels and to survey controlled delivery of medicine in pseudo-human body environments [1]. Hydrogels have been used as a base for rectal and vaginal drug delivery.Modern controlled drug de