Revenue generation from the cultivation and distribution of mango has increased over the past two decades across Sub-Saharan Africa. Experts say Ghana has the prerequisite conditions for making mango her next "gold mine". This research project therefore sought to model mango production potential of Ghana by delineating suitable areas. This will enable stakeholders to contribute meaningfully to efforts being made to convert Ghana's comparative advantage in mango cultivation into a competitive one. By superimposing the ArcGIS modelled outputs (maps), a resultant map was obtained which gave an overview of the potential locations within the respective agro-ecological zones (AEZs) with varying suitability ratings (SR) ranging from 1 (least suitable) to 10 (most suitable). Areas within the Coastal Savannah Zone (CSZ), Guinea Savannah Zone (GSZ) and the Transitional Zone (TZ) where commercial mango growing activities are known to occur could be located within this resultant map. The sum of cultivable areas (ha) with each of the 3 resulting suitability ratings; SR 2, SR 5 and SR 10 were 1,429,682 ha, 15,059,000 ha and 6,396,710 ha representing 5.9 %, 63.1 % and 26.8 % of the total land area of Ghana respectively.