Background: The aim of this study was to investigating the Psychometric properties of Hassanzadeh Life Enthusiasm Questionnaire (HLEQ) in general population. Materials and Methods: In this descriptive-survey research 450 people (225 male and 225 female) were selected via randomize simple method. In addition to the sociodemographic variables and the Hassanzadeh Life Enthusiasm Questionnaire (HLEQ),Ryffs Scale of Psychological Well-Being (RSPWB), Meaning in Life Questionnaire (MLQ), Life Regard Index (LRI), Satisfaction with Life Scale (SWLS) and Life Orientation Test (LOT) were administered. Hassanzadeh Life Enthusiasm Questionnaire (HLEQ) was developed, based on a theoretically and empirically grounded definition of life and health, to assess this construct Data were analyzed by correlation coefficient. Results: Coefficients of Cronbach's Alpha and test- retest reliability were 0.90 and 0.86 respectively. Also there was a significant relation between HLEQ, RSPWB, MLQ, LRI, SWLS and LOT scores (p<0.001). Conclusion: The HLEQ is a valid and reliable scale for assessing life enthusiasm.