The performance of wireless sensor network (WSN) can be effect by interference. The many devices in network capable of causing interference and this can cause dropping packets or block the transmission channel. In this paper we study how manage the interference in WSN. This managing can be done by flow control and power level control. We used heterogeneous collaborative network nodes like PIC microcontroller, ARM microcontroller and Personal Computer (PC) to build our network. Also we assign priority level for each node to allow the node with high priority to manage the flow and power level of other node within same network and same used channel. The time synchronization required due to different nodes used. The protocol used for time synchronization is Timing-sync Protocol for Sensor Networks (TPSN).